National Primary Route 21, or just Route 21 (, or ) is a National Road Route of Costa Rica, located in the Guanacaste, Puntarenas provinces.
Description In Guanacaste province the route covers Liberia canton (Liberia and Nacascolo districts), Nicoya canton (Nicoya and Mansión districts), Santa Cruz canton (Santa Cruz and Diriá districts), Carrillo canton (Filadelfia, Palmira, and Belén districts), Nandayure canton (Santa Rita and San Pablo districts).
In Puntarenas province the route covers Puntarenas canton (Lepanto and Paquera districts).
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