1cP-LSD, also known as 1-cyclopropanoyl-LSD or by the nickname Curie, is a psychedelic drug of the lysergamide family and an acylated derivative of lysergic acid diethylamide (LSD) which has been sold as a designer drug. It is a prodrug of LSD.
Use and effects
1cP-LSD has been used in the form of blotter tabs containing 100μg 1cP-LSD free base and pellets containing 150μg 1cP-LSD hemitartrate. Its dose is said to be 100 to 200μg and it has comparable potency to 1P-LSD and 1B-LSD. Its duration has been said to be 5 to 10hours.
Interactions
Pharmacology Pharmacodynamics 1cP-LSD is a prodrug of LSD. It has been found to produce psychedelic-like effects, specifically the head-twitch response, in rodents with similar potency as 1P-LSD.
Chemistry Analogues Related compounds include 1B-LSD, 1DD-LSD, 1P-LSD, 1V-LSD, ALD-52 (1A-LSD), 1cP-AL-LAD, AL-LAD, ETH-LAD, 1P-ETH-LAD, PRO-LAD, LSM-775, and LSZ, among others.
Society and culture Legal status
Canada 1cP-LSD is not a controlled substance in Canada as of 2025.
Sweden Sweden's public health agency suggested classifying 1cP-LSD as a dangerous substance on 18 December 2019 and later classified it as such on 22 April 2021.
United States 1cP-LSD is not an explicitly controlled substance in the United States. However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.
Research 1cP-LSD has been investigated as a potential treatment for anxiety in dogs and cats.
See also Substituted lysergamide Lizard Labs
References
External links 1cP-LSD - Isomer Design 1cP-LSD - PsychonautWiki The Small & Handy 1cP-LSD Thread - Bluelight 1cP-LSD - Lysergamide Psychedelics - TripSitter