Klasen is a surname of Dutch and German origin. Notable people with the surname include:
Anna Klasen (born 1993), German tenniswoman Arno Klasen (born 1967), German racecar driver Jacqueline Klasen (born 1994), German footballer Karl Klasen (1909–1991), German jurist and banker Linus Klasen (born 1986), Swedish professional ice hockey player Sepp Klasen (1935-2023), Germand politician Stephan Klasen (1966-2020), German economist and professor Thomas Klasen (born 1983), German footballer and current football coach
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