Cornelius Cole (1822–1924) was a U.S. Senator from California from 1867 to 1873. Senator Cole may also refer to:
Albert M. Cole (1901–1994), Kansas State Senate Albert Cole (Massachusetts politician) (1904–1966), Massachusetts State Senate Bill Cole (West Virginia politician) (born 1956), West Virginia State Senate Dan H. Cole (1811–1881), New York State Senate Ernest E. Cole (1871–1949), New York State Senate Gordon E. Cole (1833–1890), Minnesota State Senate Harry A. Cole (1921–1999), Maryland State Senate Helen Cole (1922–2004), Oklahoma State Senate Samuel Cole (politician) (1856–1935), Massachusetts State Senate Tom Cole (born 1949), Oklahoma State Senate