Senator Paine may refer to:

Elijah Paine (1757–1842), U.S. Senator from Vermont from 1795 to 1801 Ephraim Paine (1730–1785), New York State Senate George Eustis Paine (1920–1991), New York State Senate Ira Paine (1890–1966), Nebraska State Senate William W. Paine (1817–1882), Georgia State Senate

See also Senator Payne (disambiguation)