Cardium (from Greek καρδίᾱ kardiā, heart) may refer to:

-cardium, a combining form used in terms associated with the heart such as pericardium, epicardium and endocardium , a genus of molluscs in the family Cardiidae Cardium edule, now named Cerastoderma edule, the common cockle Cardium Formation, a stratigraphic range in western Canada Cardium pottery, a Neolithic decorative style