Town Creek may refer to the following places in the United States:
Communities Town Creek, Alabama, a town in Lawrence County Town Creek, Dallas, Texas, a neighborhood in the Lake Highlands area Town Creek, Maryland, an unincorporated community in Allegany County
Waterways Town Creek (Mississippi), a tributary stream of the Tombigbee River Town Creek (Chestatee River tributary), a tributary of Tesnatee Creek in Georgia Town Creek (Talking Rock Creek tributary), a stream in Georgia Town Creek (Withlacoochee River tributary), a stream in Georgia Town Creek (Patuxent River), a tributary of the Patuxent River in Saint Mary's County, Maryland Town Creek (Potomac River), a tributary of the Potomac River in Maryland and Pennsylvania Town Creek (Tred Avon River), a tributary of the Tred Avon River, Talbot County, Maryland Town Creek (Hatchie River), a tributary of the Hatchie River, Tipton County Tennessee
Other Town Creek Indian Mound, a National Historic Landmark in North Carolina
See also Blood Creek, a 2009 Joel Schumacher horror film also known as Town Creek