Lamivudine/tenofovir disoproxil (3TC/TDF), sold under the brand name Cimduo among others, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS in adults and children weighing more than . It contains lamivudine and tenofovir disoproxil. It is taken by mouth.

Lamivudine/tenofovir was approved for medical use in the United States in February 2018.

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