Gui ( or ), or Kwai () in Cantonese, is a Chinese surname. Notable people with this surname include:
Gui Minhai ( or ; born 1964), Chinese-born Swedish book publisher and writer Gwei Lun-mei (; born 1983), Taiwanese actress Gui Hong (; born 1995), Chinese footballer Gua Ah-leh (; born 1944), Taiwanese actress and singer Gui Haichao (), Chinese astronaut Nancy Kwai (; born 2000), Hong Kong singer and actress