João Infante () was a Portuguese explorer of the African coast. He accompanied Bartolomeu Dias in his journey around the Cape of Good Hope in 1487/1488 by leading a second caravel, the São Pantaleão (named after Saint Pantaleon).

Some places in South Africa are or were named after him: (public domain) The Rio do Infante, now the Great Fish River, Eastern Cape Cape Infanta, Western Cape Infanta, Western Cape: a small settlement

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