Lampugnani is a surname. Notable people with the surname include:
Gian Giacomo Lampugnani (active 2nd decade 16th century), Italian painter of the Renaissance Giovanni Andrea Lampugnani (died 1476), member of the Milanese nobility Giovanni Battista Lampugnani (c.1708–1786), Italian composer Vittorio Magnago Lampugnani (b.1951), Italian architect