Sickels is a surname. Notable people with the surname include:

Carter Sickels (born 1970s), American author and educator Emma Cornelia Sickels, (1854–1921), American teacher Frederick Ellsworth Sickels (1819–1895), American inventor Garrett Sickels, American footballer John Sickels (b. 1968), American baseball writer Quentin Sickels, American footballer

See also Sickles, a surname with alternative spelling

See also Sickel Sickle (disambiguation)