The Clarksdale Walk of Fame honors notable people from Clarksdale, Mississippi who have made their mark on the culture of Clarksdale. It was created in 2008 by the Clarksdale/Coahoma County Chamber of Commerce as a self-guided walking tour in an effort to increase foot traffic in downtown Clarksdale. The plaques are located near a site of historical significance associated with the honoree. Singer Sam Cooke received the first plaque, dedicated outside the New Roxy theater where he once performed.

Also in Clarksdale is the Blues Alley Walk of Fame which was a precursor to the Clarksdale Walk of Fame. Blues musician John Lee Hooker and the Texas-based rock band ZZ Top were honored. ZZ Top helped raise $1 million in support of the Delta Blues Museum, they have a plaque at the Carnegie Public Library (former location of the museum).

Inductees +HonoreeLocationSam CookeNew Roxy Theater, 357 Issaquena AvenueSon HouseCat Head Delta Blues & Folk Art, 252 Delta AvenueMuddy WatersClarksdale Station Train Depot, Blues AlleyTennessee WilliamsSt. George's Episcopal Church Rectory, 108 Sharkey AvenueJohn ClarkClark House, 211 Clark StreetEarly WrightAlcazar Hotel, 127 Third StreetCharlie ConerlyHambone Art Gallery, 111 East 2nd StreetPerian ConerlyHambone Art Gallery, 111 East 2nd StreetAaron HenryMartin Luther King Boulevard and Ashton AlleyIke TurnerDelta Blues Museum, 1 Blues AlleySuper ChikanGround Zero Blues Club, 0 Blues AlleyBig Jack JohnsonRed's Blues Club, 398 Sunflower Ave

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