Koskoff is a surname. Notable people with the surname include:

David Koskoff (born 1939), American attorney and author Emma Tillinger Koskoff (born 1972), American film producer Gertrude Koskoff (1911–1992), American politician Milton Koskoff (1907–1997), American politician Theodore I. Koskoff (1920–2007), American trial lawyer

See also Kosoff Kossoff