Yacoubian is an Armenian surname. Notable people with the surname include:
Hagop Yacoubian, proprietor of the Yacoubian Building in Cairo, Egypt Paula Yacoubian (born 1976), Lebanese journalist, TV personality, politician and Member of Parliament Yacoub Yacoubian, proprietor of the Yacoubian Building in Beirut, Lebanon
See also Yacoubian Building (disambiguation)