Nusser or Nüsser is a surname. Notable people with this name include:

Josef Mayr-Nusser (1910–1945), Catholic martyr for refusing to become a Nazi soldier Andrés Nusser, founding member of Astro (Chilean band) Franz Nusser, Austrian meteorologist, namesake of Nusser Island James Nusser (1905–1979), actor in Gunsmoke Josef Nüsser (1931–2023), Czech skier and Olympian Larissa Nüsser (born 2000), Dutch handball player Laura Nusser, victim of serial killer Vincent Johnson Robert Nusser (1931–2001), Austrian ice hockey player and Olympian Sarah Nusser (born 1957), American statistician Zoltan Nusser, Hungarian physiologist

See also Nußhardt, a German mountain also sometimes called Nusser