Arregui is a surname. Notable people with the surname include:
Adrián Arregui (born 1992), Argentine footballer Antonio Arregui Yarza (1939–2026), Catholic Archbishop of Guayaquil, Ecuador Brian Arregui (born 2000), Argentine boxer Carolina Arregui (born 1965), Chilean television actress Celinda Arregui (1864–1941), Chilean feminist politician, writer, teacher, suffrage activist Facundo Arregui (born 1997), Argentine Paralympic swimmer Felipe Arregui (born 1994), Argentine rugby union player Joseba Arregui Aramburu (1946–2021), Spanish politician, theologian, and academic Juan de Arregui (1656–1736), Spanish Franciscan priest and Roman Catholic Bishop of Buenos Aires Olatz Arregui (born 1999), Spanish slalom canoeist Ricardo Arregui (born 1952), Spanish surgeon, frostbite specialist and former president of CAI Balonmano Aragón and Asobal Handball League