A1A may refer to:

Florida State Road A1A A1A (album), a 1974 album by Jimmy Buffett Alpha-1 antitrypsin, a protease inhibitor secreted by the liver Several branches of A1 motorway in Switzerland numbered as A1a, located separately in Geneva, Lausanne and Vaud Continuous wave modulation with Morse code

See also A1A-A1A, an AAR wheel arrangement in locomotives