Cottone is a surname of Italian origin. Notable people with this surname include:
Antonio Cottone (1904/1905–1956), Italian member of the Sicilian Mafia Benedetto Cottone (1917–2018), Italian politician Carlo Cottone, prince of Castelnuovo, (1756–1829), Italian politician, advocate of the Sicilian Constitution of 1812 Jay Cottone (born 1949), American football player Maegan Cottone, British American songwriter, singer, vocal producer and vocal arranger Robert Rocco Cottone (born 1952), American psychologist, ethicist, counselor, poet, and professor
See also Cotton (surname)