OSM may refer to:
Software and websites OpenStreetMap, an open source project to develop free geographic data Open Service Mesh, a free and open source cloud native service mesh
Organizations Austrian Student Mission () Office of Surface Mining, a branch of the US Department of the Interior OSM TV, a Bosnian commercial television channel Montreal Symphony Orchestra (), a Canadian symphony orchestra
Science Oncostatin M, a protein Osmole (unit), a unit of osmotic concentration Osmotic avoidance abnormal protein, for example OSM-9
Transportation Honda OSM, a 2008 Japanese concept sports car Mosul International Airport, Iraq, IATA airport code OS-M, a series of space launch rockets from OneSpace
Other uses Operational Service Medal (disambiguation), multiple campaign medals Order of the Secret Monitor, an appendant order of Freemasonry O.S.M., the post-nominal letters used by members of the Servite Order OSM Worldwide, a parcel delivery service One Saturday Morning, a former Saturday morning cartoon block on ABC