Portlock is a surname. Notable people with the surname include:
Jenice Dena Portlock (born 1987), also known as Sabi, is an American pop singer, songwriter, dancer and actress Joseph Ellison Portlock (1794–1864), British geologist and soldier Nathaniel Portlock (c. 1748–1817), British ship’s captain, maritime fur traderand author
See also Portlock, Alaska, is a ghost town in the U.S. state of Alaska