The manga series Dr. Stone features an extensive cast of characters created by Riichiro Inagaki and Boichi.
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Main characters Senku Ishigami
is a teenage prodigy who excels in multiple fields of science, with a special love of astronomy and space exploration. After awakening in the "Stone World", he sets out to restore civilization by reinventing their lost technology and discovering a "cure" for the petrification. Though somewhat arrogant, he is very noble and kind-hearted as he considers science as a means to elevate all people and has unshakable faith in his friends. After faking his death to keep Tsukasa from hunting him, Senku befriends the residents of Ishigami Village and becomes their chief, finding out that he is a legend in the village's community at the same time thanks to the influence through one of the villagers' ancestors, who happens to be Senku's late adoptive father Byakuya, one of the original petrification survivors. Following Hyoga's defeat and Tsukasa entering cryosleep, Senku was able to get the remnants of the Empire of Might to merge with the Kingdom of Science where he leads the Five Wise Generals. He has Albert Einstein's formula (E = mc2) as his trademark.
Taiju Oki
is Senku's best friend, whom Senku refers to as a "big oaf" or "musclehead". He has incredible strength and seemingly limitless stamina with the awareness of a pacifist who's never thrown a punch in his life, preferring to turn the other cheek instead to prevent any assailants from hurting his friends. He is in love with Yuzuriha and will do anything to take care of her, especially when she's in danger. Taiju is a typical high schooler and simply believes smartphones are an important tool for civilization. After Senku fakes his death to keep Tsukasa from hunting them, Taiju and Yuzuriha infiltrate the Tsukasa Empire to keep tabs on Tsukasa before rejoining Senku in Ishigami Village. As a member of the Power Team, Taiju leads its farming division while assisted by Yō and Magma.
Yuzuriha Ogawa
is Taiju's love interest, a cheerful and kind-hearted young woman. She enrolled in her high school's handicrafts club to pursue her goal of becoming a fashion designer and is exceptionally talented at arts like stitching and clothwork. Moments before the petrification light, Taiju is about to confess to Yuzuriha, so she patiently waits to return them officially when the quest to rebuild civilization is resolved. During the "Vs. Tsukasa" arc, Tsukasa takes Yuzuriha captive. Senku has her and Taiju spy within the Tsukasa Empire as part of his plan till the next year when the cell phone is buried in Senku's fake gravestone. During the "Age of Exploration" arc, Yuzuriha started a clothing store joining the Craftsmanship and Development Team. She and Taiju got married after the Moon-Landing project.
Tsukasa Shishio
is a youth who rose to fame in mixed martial arts as "The Strongest Primate High Schooler", being physically powerful enough to kill a lion with one punch. After being reawakened by Senku to save him and Taiju from a lion pack, Tsukasa wears the pelt of the male lion he killed while hunting for Senku and Taiju. He resents adults due to his experience with one who prevented him from gathering seashells for his comatose sister Mirai, viewing the current adults as avaricious corruption while seeking to create a new society in the "Stone World" by only reviving young people. Tsukasa serves as the primary antagonist of the early story arcs, appearing to kill Senku when he refuses to back down from restoring their civilization before proceeding to establish his Empire of Might. Through the revived Gen to confirm Senku's death, Tsukasa remained in the dark about his opposition's survival until he learned it from Hyoga. During the "Communications" arc, Tsukasa accepted a truce with Senku in exchange for the theoretical revival of his sister, after which Hyoga betrayed him. The critical injuries Tsukasa suffered from the fight forced him to be placed in cryosleep with his remaining forces absorbed into the Kingdom of Science. However, he does get to see Mirai get restored to good health beforehand. When Tsukasa is revived, he sides with Senku accompanied on his trip to the United States of America while still striving for a morally pure world where the innocent will not be exploited.
Kohaku
is the strongest warrior of Ishigami Village and Ruri's younger sister, a tomboyish young woman who is exceptionally strong, agile, and sharp-eyed. She is the first villager Senku meets after awakening in the "Stone World" and becomes one of his staunchest allies as part of the Kingdom of Science's Power Team. A running gag is when her femininity is insulted for being called a gorilla or a lioness. She shows good caring towards her friends and comrades, particularly Suika. Kohaku enjoys the concept of romance and does not mind the idea of being betrothed to Senku despite his lack of interest. She once kissed Senku as part of a distraction on Treasure Island.
Chrome
is a youth from Ishigami Village who named himself the village's self-proclaimed sorcerer when stumbled upon the basics of science and mistook them as sorcery, wanting to cure Ruri. His hobby of rock collecting and managing chemical reactions stems from the Hundred Tales. Chrome later learns about the scientific wonders of the old world and becomes Senku's partner as he helps him rediscover humanity's scientific legacy. When the Kingdom of Science and the remnants of the Tsukasa Empire merge, Chrome becomes one of the Five Wise Generals and a part of the Craftsmanship and Development Team. He has had multiple failed attempts to confess his affection to Ruri, until finally proposing to her (in an underwhelming manner) and getting married in the 4D manga.
Suika
is a young girl from Ishigami Village who wears a watermelon on her head to cover up her "fuzzy sickness". She ends up gravitating to Senku, helping him as he is the first person not to judge her for her eccentricities before he outfitted her watermelon helmet with customized lenses. Suika often helps Senku out by being a scout for different missions where she can withdraw into her watermelon helmet. Following the merging of the Kingdom of Science and the Tsukasa Empire, Suika became a member of the Intelligence Team. After the second worldwide petrification event, Suika is the only person to be released as part of a contingency put in place by the Kingdom of Science. As she grows into a teenager in the following seven years, she works alone to recreate the revival fluid, successfully bringing Senku and the others back.
Gen Asagiri
is another person from the "old world", Gen is a silver-tongued self-help guru who styles himself as a mentalist. Gen wears an overcoat over his yukata and is always barefoot except in the winter. He was revived by Tsukasa who wanted an ally who could think like Senku and confirm his death. But being self-serving, Gen ends up defecting to the Kingdom of Science after witnessing Senku's accomplishments. He is confident in his tactics as a proficient manipulator, although this facade is not always present as Gen appears to react freely in shock whenever Senku brings up his next planned invention. When the Kingdom of Science and the remnants of the Empire of Might merge following the defeat of Hyoga and Tsukasa entering cryosleep, Gen becomes one of the Five Wise Generals.
Ryusui Nanami
Ryusui Nanami is the patriarch and youngest son of Nanami Conglomerate's owner who was revived by Senku in the "Age of Exploration" arc to be part of the Kingdom of Science as one of the Five Wise Generals. His personality is akin to that of a self-indulgent rich boy fueling his ambition to earn success through his own talent which Minami finds rather annoying and in contrast to Tsukasa's preference. Ryusui spends his allowance on model ships and is active in sailing any type of ship. As an expert sailor, he was made the Captain of the Perseus which he helped build as part of the Craftsmanship and Development Team. Like Senku, Ryusui has the drive to rebuild society aside from his proclamation as leader of the new world.
Recurring characters Kingdom of Science and Tsukasa Empire When Tsukasa was revived and had some differences with Senku, two factions arose. The was made by Senku to recreate the scientific achievements in the world. The or Empire of Might was made so the strong could rule. When Hyoga was defeated and Tsukasa entered cryosleep, the remnants of the Tsukasa Empire merged with the Kingdom of Science which later gained new members from those who were freed from their petrification.
Hyoga is a tall and fairly built spear-armed man who is strong enough to take on 10 attackers. He is revived by Tsukasa during the "Vs. Hyoga" arc. Hyoga and some Tsukasa Empire fighters took on the Ishigami Village's finest until it was discovered that Gen rigged their weapons. Hyoga himself is an elitist who believes in social Darwinism. After Mirai's revival, he betrays Tsukasa causing an unlikely team-up between Senku and Tsukasa to defeat him. The imprisoned Hyoga had to accompany Senku who needed some additional muscle. Later, in the "Treasure Island" arc, Senku revives Hyoga to fight against Moz, only for them to both get petrified by Ibara, causing him to be a statue again. In the "South America" arc, Hyoga is reformed and officially joins the Power Team.
Homura is a member of the Tsukasa Empire who was a gymnast prior to the petrification and is the right-hand to Hyoga. Homura was released from her petrification and has an allegiance to Hyoga. Homura assisted Hyoga in the first attack on Ishigami Village where she snuck into the village and set fire to some of the huts. Her gymnastics prowess means her speed and agility are more than a match to Kohaku's. During the "Communications" arc, she did some surveillance on Ishigami Village. When Homura tried to sabotage the radio tower, Magma and Kinro cut the tree enabling Kohaku to catch her. Homura did manage to cave-in the Miracle water obscure the revival fluid. During the "New America" arc, Homura had to accompany Senku who needed some additional muscle.
Minami was a journalist prior to petrification who knew famous people. After being released from her petrification, Minami serves Tsukasa where she wears a leather dress and is always barefoot. She is heavily enamored with Tsukasa. Both of them agree that the world before the petrification was awful. When Hyoga was defeated and Tsukasa entered cryosleep, Minami was among those who joined the Kingdom of Science where she joined their Intelligence Team. During the "Age of Exploration" arc, Minami and Gen bargain for the stone formula so that they can reawaken Francois to recreate the camera. She wastes no time in chronicling Perseus voyage.
Ukyo Saionji is an SDF Navy sailor and submarine sonar operator who was released from petrification by Tsukasa. He is an expert in different languages and has super-sensitive hearing. When he worked with Tsukasa, Ukyo became an expert archer and one of Tsukasa's scouts. During the "Communications" arc, Ukyo attacked Chrome, Gen, and Magma while setting up telephone poles which ended with him capturing Chrome. When Senku and Gen made contact with him, Ukyo agreed to their terms in exchange for a "no death" rule due to Tsukasa shattering petrified humans and suspecting that Hyoga had sacrificed their fellow warriors to the sulfur gas. Following Hyoga's defeat and Tsukasa entering cryosleep, Ukyo is among those who join the Kingdom of Science where he becomes one of the Five Wise Generals. /