James Crombie may refer to:
James Crombie (minister) (1730–1790), Scottish Presbyterian minister, founder of Belfast Academy James Crombie (politician) (1834–1898), politician in colonial Queensland James Edward Crombie (1862–1932), Scottish philanthropist, meteorologist and seismologist James Crombie (civil servant) (1902–1969), English civil servant James Mascall Morrison Crombie, Scottish lichenologist James Crombie (badminton), Scottish badminton player