Sergius I of Cyrrhus was a bishop of Cyrrhus, a Roman city in what is today Syria.Raymond Janin, v. Cyrrhus in Dictionnaire d'Histoire et de Géographie ecclésiastiques, vol. XIII, Paris 1956, coll. 1186-1187 He lived at a time when Cyrrhus was the center of a number of theological controversies, that birthed the Nestorian and Jacobite churches.
He was a late 5th century Nestorian bishop and was deposed by Byzantine Emperor Justin I in the theological controversies following the first four ecumenical councils. Sergius I of Cyrrhus was replaced by another bishop called Sergius II, who was of the directly opposite theological opinion, being a Jacobite. This bishop was subsequently expelled in 522 and replaced by an Orthodox bishop.
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