Governor Mathews or Matthews may refer to:
George Mathews (Georgia) (1739–1812), 16th Governor of Georgia Henry M. Mathews (1830s–1884), 5th Governor of West Virginia John Mathews (lawyer) (1744–1802), 33rd Governor of South Carolina Samuel Mathews (Colonial Virginia governor) (1630–1660), Commonwealth Governor of Virginia from 1656 to 1660 Claude Matthews (1845–1898), 23rd Governor of Indiana Joseph W. Matthews (1812–1862), 15th Governor of Mississippi
See also Edward Mathew (1729–1805), Governor of Grenada from 1782 to c. 1797