Upītis (feminine: Upīte) is a Latvian masculine surname, derived from the Latvian word for "river" (upe). Individuals with the surname include: Ernests Birznieks-Upītis (1871–1960), Latvian writer, translator and librarian Juris Upītis (born 1991), Latvian ice hockey player Pēteris Upītis (1896–1976), Latvian horticulturist Pēteris Upītis (1899–1989), Latvian graphic artist and art collector