Melaku is an Ethiopian name. Notable people with the name include:
Given name Melaku Belay, leader of the Ethiopian music group Fendika Melaku Worede (1936–2023), Ethiopian agronomist
Surname LoLa Monroe (born Fershgenet Melaku in 1986), American rapper, model and actress of Ethiopian descent Tsega Melaku (born 1968), Israeli author, journalist, and community activist