John Isaacs (1915–2009) was an American professional basketball player who was inducted into the Basketball Hall of Fame.
John or Jon Isaacs may also refer to: John Alfred Isaacs (c. 1861–1944), Victoria, Australia politician John Dove Isaacs (1919–1980), American engineer and oceanographer John O. Isaacs (1920–2001), English aeronautical engineer Jon Isaacs (born 1949), Australian politician
See also John Isaac (disambiguation)