Ossola may refer to:
Ossola, an area of Italy situated to the north of Lago Maggiore, in the Province of Verbano-Cusio-Ossola
People Aldo Ossola (born 1945), Italian former basketball player Franco Ossola (1921–1949), Italian forward footballer Irena Ossola (born 1988), American professional racing cyclist Luigi Ossola (1938–2018), Italian professional football player Raffaello Ossola (born 1954), Swiss-born Italian surrealist painter Rinaldo Ossola (1913–1990), Italian economist and politician