Topisaw is an unincorporated community in Pike County, in the U.S. state of Mississippi.
History The community takes its name from Topisaw Creek, which flows near the site. Topisaw Creek is derived from the Otapasso tribe that lived in the area. A variant name is "Carters Creek". A post office called Topisaw was established in 1880, and remained in operation until 1905. In 1900, Topisaw had a population of 46.
The Topisaw Church, also known as Felder Church, originally started as a camp meeting in 1845.
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