Esplin is a Scottish surname. Notable people with the surname include:
Donald Esplin, Australian architect, designer of The Astor in Sydney in 1923 Mabel Esplin (1874–1921), British stained glass artist Ron Esplin (born 1944), American Mormon historian
See also Esplin Islands, a group of two small islands and off-lying rocks lying northeast of Box Reef, off the south end of Adelaide Island Asplin