Prince John may refer to:
John, King of England (1166–1216) known as Prince John during the reigns of his father and older brother Prince John of the United Kingdom (1905–1919), youngest son of King George V John of Eltham, Earl of Cornwall (1316–1336), second son of Edward II John of Gaunt, 1st Duke of Lancaster (1340-1399), third son of Edward III John of Lancaster, 1st Duke of Bedford (1389–1435), second son of Henry IV John, Prince of Asturias, (1478–1497), only son of Ferdinand II of Aragon and Isabella I of Castile Prince Alexander John of Wales (1871), third son and youngest child of Edward VII Prince John Konstantinovich of Russia (1886–1918), great-grandson of Nicholas I of Russia Prince John August of Saxe-Gotha-Altenburg (1704–1767), son of Frederick II, Duke of Saxe-Gotha-Altenburg
Other Nickname of Confederate general John B. Magruder Prince John (horse), champion racehorse