Pantaleo is an Italian name. Saint Pantaleon or Pantaleo was a 4th century saint, whose veneration was widespread in Italy. Notable people with the name include:
Surname Mario Pantaleo (1915–1992), Italian priest who lived most of his life in Argentina Rocco Pantaleo (1956–2010), Italian restaurateur Daniel Pantaleo, NYPD officer responsible for the killing of Eric Garner
Given name Pantaleo Carabellese (1877–1948), Italian philosopher Pantaleo Corvino (b. 1949), Italian director of football (soccer)
See also Pantaleon (disambiguation) Pantalone, a commedia dell'arte character