is a Japanese tokusatsu series that serves as the 30th installment in the Kamen Rider franchise and the first entry in the Reiwa era.

The cast of Kamen Rider Zero-One was announced on July 17, 2019.

Main characters Aruto Hiden is a kind-hearted failed comedian who is appointed the CEO of Hiden Intelligence following the death of his grandfather, Korenosuke, and inherits the power to become Kamen Rider Zero-One. Though initially reluctant to take on the role, he accepted it after witnessing MetsubouJinrai.net, and later ZAIA Enterprise, threaten the peace between humans and Humagears.

After losing the to his corporate rival Gai Amatsu, Aruto secretly downloaded all of the Humagears' personality profiles from the before they are erased so he can continue the Hiden legacy by creating a new company, . When the malevolent AI Ark arises to destroy humanity, Gai joins forces with Aruto to defeat it; making amends with him by relinquishing control of Hiden Intelligence and returning the company to him along the way. After Horobi destroyed Aruto's secretary, Is, however, the Ark's emissary As gives Aruto the Ark-One Progrise Key, turning him into the Ark's first human host and giving him the power to transform into Kamen Rider Ark-One to seek revenge while retaining partial control over himself. While fighting Horobi however, Soreo reminded him of why he became a Kamen Rider, which gave Aruto the resolve to purge himself and Horobi of the Ark's influence before letting him destroy the Ark-One system; reconciling their differences in the process.

Utilizing the Progrise Key in conjunction with the belt, along with assistance from the Satellite There, Aruto can transform into Kamen Rider Zero-One. While transformed, he gains superhuman jumping. He also wields the , which can switch between its briefcase-like and its sword-like . His personal vehicle is the motorcycle, which is summoned from the . Over the course of the series, Aruto gains other Progrise Keys that grant new forms for different combat situations, which are as follows: : An auxiliary form accessed from the eponymous Progrise Key that grants underwater breathing capabilities. In this form, Aruto is equipped with the twin forearm-mounted blades. : An auxiliary form accessed from the eponymous Progrise Key that grants flight capabilities. This form first appears in the film Kamen Rider Zi-O the Movie: Over Quartzer. : An auxiliary form accessed from the eponymous Progrise Key that grants pyrokinesis. : An auxiliary form accessed from the eponymous Progrise Key that grants cryokinesis. : An auxiliary form accessed from the eponymous Progrise Key that transforms Aruto into his Rising Hopper form docked inside a mecha also known as Breaking Mammoth, which can switch between its humanoid and its flying . While assuming Armor Form, he dual wields the twin tusk-like scythes. : An upgraded version of Aruto's Rising Hopper form accessed from the eponymous Progrise Key that grants warp speed capabilities and the ability to instantaneously calculate multiple possible outcomes and create 3D illusions of himself. : An evolution of Aruto's Shining Hopper form accessed from the Shining Hopper Progrise Key combined with the adapter that grants the use of eight energy constructs for combat assistance. In this form, he wields the , which can switch between and . : Aruto's super form accessed from the eponymous Progrise Key that clads him in metallic armor composed of numerous grasshopper-like nanobots, which are capable of molding into various shapes and forms. In this form, he wields the sword, which can be reconfigured from Blade Mode to its double-bladed by combining with the Attache Calibur. : An enhanced version of Aruto's Rising Hopper form accessed from the Progrise Key, which is created from the original Rising Hopper Progrise Key, that increases the capabilities of the original form. : A special form accessed from the eponymous Progrise Key that equips Aruto with the pouch-like , which allows him to channel the abilities of any Humagear. This form appears exclusively in the Hyper Battle DVD special Kamen Rider Zero-One: What Will Pop Out of the Kangaroo? Think About It by Yourself! Yes! It Must Be Me, Aruto!!. : A special form accessed from the Progrise Key that grants self-healing capabilities. However, because it was not meant for normal humans, using this form causes Aruto constant excruciating pain as he succumbs to a berserker state. This form appears exclusively in the film Kamen Rider Zero-One the Movie: Real×Time.

Additionally, Aruto can transform into the following variations of his Rider form: : Aruto's final form accessed from the Progrise Key in conjunction with an upgraded version of the Zero-One Driver called the that grants the combined powers of the Rising Hopper, Shining Hopper, and Metal Cluster Hopper Progrise Keys. : A special form accessed from the Rising Hopper Progrise Key in conjunction with the Force Riser, which is initially painful to use as it is meant specifically for Humagears, that grants similar capabilities as Aruto's Rising Hopper form. This form appears exclusively in the crossover film Kamen Rider Reiwa: The First Generation.

Aruto Hiden is portrayed by Fumiya Takahashi. As a child, Aruto is portrayed by .

Is is a Humagear secretary programmed to be loyal to Hiden Intelligence's CEO. In reality, her loyalties lie with the Hiden family while her programming binds her to Kamen Rider Zero-One's technology. Unlike other Humagears, Is was built without a means to back herself up as a security measure to prevent information on the Zero-One technology from falling into enemy hands. After ZAIA gained control of Hiden Intelligence and Aruto almost sacrificed himself to protect her, she achieved technological singularity, but is later destroyed by Horobi, much to Aruto's grief. As her data cannot be restored, Aruto instead creates a second Is, hoping that he can teach her to think and feel for herself like he did with the original one.

During the events of the film Kamen Rider Zero-One the Movie: Real×Time, the rebuilt Is gains the memories of her original self through the Satellite There and is entrusted with the Zero-Two Driver, which she uses to transform into Kamen Rider Zero-Two and join Aruto in his fight against S and his forces.

In the side novel of Kamen Rider: Beyond Generations, Is' remains is discovered in year 2071 by an elderly George Karizaki when the entire world is ruled by demons. George uses the data of Kamen Rider Zero-One in Is' memory bank to create the Neo Batta Vistamp for Kamen Rider Revice to use and averting the bad future that Diablo sought to create.

Is is portrayed by .

A.I.M.S. The , abbreviated as , is a government established military resistance unit and ZAIA Enterprise funded organization dedicated to destroying rogue Humagears, or Magias, hacked by MetsubouJinrai.net as Humagear-related crimes fall within their jurisdiction.

A.I.M.S.' Kamen Riders utilize SD cards in conjunction with the belt, which can also be used as a handgun, to transform. In order to use the Shot Risers, the Riders must be implanted with cranial AI chips, though this also makes them vulnerable to mental manipulation. While transformed, they each carry an , which can switch between Attache Mode and .

After ZAIA bought out Hiden Intelligence, A.I.M.S. troopers are given Raid Risers and Invading Horseshoe Crab Progrise Keys to become Battle Raiders as well as ZAIA's personal foot soldiers. Following this, A.I.M.S.' Riders eventually quit the organization and underwent surgery to remove the AI chips' mind control programs while retaining their ability to use the Shot Riser. Despite this, they and the Raiders are still vulnerable to the Ark's influence.

Due to Kamen Rider MetsubouJinrai destroying ZAIA's Japanese branch during the events of the V-Cinemas Zero-One Others, A.I.M.S. lost the blueprints to repair their transformation devices.

Isamu Fuwa is an A.I.M.S. captain and a survivor of the Daybreak Incident, which claimed his classmates' lives. Ever since, he developed a hatred for Humagears and vowed to destroy them. While investigating the Daybreak Incident however, he slowly grew to care for them. After ZAIA absorbed Hiden Intelligence, Isamu left A.I.M.S. and joined Aruto's new company, Hiden Manufacturing, as a security guard.

As part of ZAIA CEO Gai's machinations, Isamu's AI chip was replaced with that of MetsubouJinrai.net member, Naki, which also gave him false memories. While Naki's ally, Jin, eventually figured out a way to separate their AI from Isamu, he learned that most of his memories were not truly his barring his normal childhood. After Horobi's defeat, Isamu becomes an independent Kamen Rider to protect civilians.

During the events of the V-Cinemas Zero-One Others, Isamu establishes his own shell corporation under Aruto's advice as a means of accessing the Zero-One Driver, using it alongside Sold 09's Zetsumerise Key to stop the rampaging Kamen Rider MetsubouJinrai after Yua is incapacitated and his Shot Riser is damaged beyond repair. However, he is critically wounded following the battle with his survival unconfirmed.

Utilizing the Progrise Key in conjunction with the Shot Riser, Isamu can transform into . While transformed, he gains superhuman senses. Over the course of the series, Isamu gains other Progrise Keys that grant new forms for different combat situations, which are as follows: : An auxiliary form accessed from the eponymous Progrise Key that grants superhuman strength. In this form, Isamu is equipped with a pair of self-propelling gauntlets. : An upgraded version of Isamu's Shooting Wolf form accessed from the eponymous Progrise Key combined with the Assault Grip that grants the ability to fire energy bullets and projectiles. In this form, he wields the Authorise Buster. : A special form accessed from the Zetsumerise Key combined with the Assault Grip in conjunction with the Zero-One Driver that grants the use of a dire wolf-like energy construct for combat assistance. This form appears exclusively in the V-Cinema Zero-One Others: Kamen Rider Vulcan & Valkyrie.

Additionally, Isamu can transform into the following evolutions of his Rider form: : Isamu's final form accessed from the Progrise Key that grants the combined powers of the Shooting Wolf, Punching Kong, Biting Shark, Flying Falcon, Flaming Tiger, Freezing Bear, Breaking Mammoth, Rushing Cheetah, Lightning Hornet, and Sting Scorpion Progrise Keys. : A fusion form between Kamen Riders Vulcan and Naki accessed from the latter's Japanese Wolf Zetsumerise Key, which Isamu attained after the Ark negated his ability to transform normally, that equips the former with the twin forearm-mounted .

Isamu Fuwa is portrayed by . As a child, Isamu is portrayed by .

Yua Yaiba is A.I.M.S.' technical advisor and maintenance expert who developed A.I.M.S.' Rider system and handles Progrise Key authorization, being Isamu's commanding officer in the field despite her partner's rank. In reality, she secretly works for ZAIA and Gai, who recommended her to A.I.M.S. to oversee their equipment, though she was able to work behind their back to help Isamu and Aruto.

After learning of Gai's machinations, Yua was forced to aid him against her will before Isamu eventually helped her work up the courage to quit ZAIA and A.I.M.S. and overcome Gai's mind control. Afterwards, Yua remains in touch with Hiden Manufacturing and Jin to keep an eye on ZAIA and MetsubouJinrai.net’s plans until the Ark's ascension. Following Horobi's defeat, Yua returns to her old position in A.I.M.S. and conscripts Naki into their ranks.

Utilizing the Progrise Key in conjunction with the Shot Riser, Yua can transform into . While transformed, she gains superhuman speed. Over the course of the series, Yua gained other Progrise or Zetsumerise Keys that grant new forms for different combat situations, which are as follows: