Georgios Pentzikis (Greek: Γεώργιος Πεντζίκης) was a Greek chieftain of the Macedonian Struggle.

Biography He was born in the mid-19th century in Thessaloniki and was a doctor.Παύλος Νταφούλης, Η υγειονομική περίθαλψη κατά την ένοπλο φάση του μακεδωνικού αγώνος (1904-1908) και η δράση των εφέδρων και μόνιμων αξιωματικών του υγειονομικού που συμμετείχαν στον μακεδονικό αγώνα, Διδακτορική διατριβή, University of Ioannina, Ioannina 2007, p. 274.

In 1898 he joined the Philoptochos Brotherhood of Men of Thessaloniki, which was a Greek patriotic organization that was active since 1871 and acted against several Bulgarian actions in Thessaloniki.

In 1905 the Brotherhood with Athanasios Souliotis was placed in the "Executive" of the Hellenic Organization, who even took over the leadership and managed to become a major member of the Macedonian Committee in Thessaloniki.Παύλου Λ. Τσάμη, Μακεδονικός Αγών, ΕΜΣ, Thessaloniki 1975, p. 158.Γ.Χ. Μόδης, Μακεδονικός Αγών και Μακεδόνες αρχηγοί, ΕΜΣ, 2nd version, Thessaloniki 2007, p. 115. As the head of the executive branch, he collaborated with Athanasios Vogas, Ioannis Emiris, Theodoros Zlatanos, Athanasios Kallidopoulos, Georgios Divolis, Evangelos Doumas, Argyrios Zachos, Dimitrios Margaropoulos and others in operations within the city of Thessaloniki and the surroundings against specific Bulgarian targets until 1908, when the Young Turk Revolution led to the end of the Macedonian Struggle.Συλλογικό, Θεσσαλονίκη - Επιστημονική επετηρίδα του Κέντρου Ιστορίας Θεσσαλονίκης του Δήμου Θεσσαλονίκης, Vol. III, Thessaloniki 1992, p. 194, 198. During this period, he was in danger of being imprisoned by the Ottoman authorities after a strike against a Bulgarian target, but after actions of the organization for his acquittal he managed to get rid of the accusations and continue his actions.Γ.Χ. Μόδης, 2007, p. 111-112.

For his contribution as leader and coordinator of the "Executive", Pentzikis was recognized as an Agent II Class and at the same time he was awarded the Silver Cross of the Order of the Redeemer.Ιωάννης Σ. Κολιόπουλος (scientific diligence), Αφανείς, γηγενείς Μακεδονομάχοι, Εταιρεία Μακεδονικών Σπουδών, University Studio Press, Thessaloniki, 2008, p. 54Γενικό Επιτελείο Στρατού, Διεύθυνσις Ιστορίας Στρατού, Ο Μακεδονικός Αγών και τα εις Θράκην γεγονότα, Athens 1979, p. 210Αρχείο Διεύθυνσης Εφέδρων Πολεμιστών, Αγωνιστών, Θυμάτων, Αναπήρων, Αρχείο Μακεδονικού Αγώνα, φ. Π-548.

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