Great Work or great work may refer to:
A masterpiece or magnum opus, a creation that has been given much critical praise Magnum opus (alchemy), the process of working with the prima materia to create the philosopher's stone Great Work (Hermeticism), also known as magnum opus, a term used in Hermeticism Great Work (Thelema), a term used in Thelema
See also Magnum opus (disambiguation)