Plotius may refer to:
Plotius, synonym for the spider genus Euryattus Plotius, alternative spelling of Plautius, nomen of the Plautia gens, a Roman family Lucius Plotius Gallus (1st century BC), Roman rhetorician Plotius Tucca (1st century BC), Roman poet Plotius Firmus (1st century AD), Roman senator Plotius Pegasus (1st century AD), Roman senator Plotius Grypus, suffect consul in AD 88 Marius Plotius Sacerdos (3rd century AD), Roman grammarian