Serpa is a surname. Notable people with the surname include:
Adhemar Serpa (1898–1978), Brazilian water polo player Enrique Serpa (1900–1968), Cuban writer Horacio Serpa (1943–2020), Colombian lawyer and politician Innocentius Serpa (1573–1625), Italian Roman Catholic bishop Ivan Serpa (1923–1973), Brazilian painter, draftsman, printmaker, designer and educator Jorge Enrique Serpa Pérez (1942–2026), Cuban Roman Catholic bishop José Serpa (born 1979), Colombian road racing cyclist Louise Serpa (1925–2012), American rodeo photographer Marcello Serpa (born 1963), Brazilian advertising executive Patricia Serpa (born 1948), American politician Ronal W. Serpas (born ), American police chief Vasco Serpa (born 1971), Portuguese sport sailer
See also Serpas