Coxie is a Flemish surname. Notable people with this surname include:
Albert de Coxie (died 1709), Spanish Netherlands politician Damonte Coxie (born 1996), American Canadian football player Jan Anthonie Coxie (c. 1660–1720), Flemish painter Jan Coxie (1629–1670), Flemish painter Michiel Coxie (1499–1592), Flemish painter Raphael Coxie (c. 1540–1616), Flemish painter