Panizo is a surname. Notable people with the surname include:
Arnaldo Panizo (1839–1892), Peruvian general Daniel Calvo Panizo (born 1979), Spanish footballer Gregolry Panizo (born 1985), Brazilian road bicycle racer José Luis Panizo (1922–1990), Spanish footballer José Panizo (wrestler) (born 1936), Spanish wrestler Juliana Panizo Rodríguez (1947–2024), Spanish academic