Nepomuceno is a surname meaning "of Nepomuk", a tribute to John of Nepomuk. Notable people with the surname include:
Alberto Nepomuceno (1864–1920), Brazilian composer and conductor Bryan Matthew Nepomuceno (born 1980), Filipino lawyer, politician and businessman Daniel Nepomuceno Navarro (born 1991), American soccer player David Nepomuceno (1900–1939), Filipino sprinter Francis Nepomuceno (born 1951), Filipino politician Francisco Nepomuceno (1916–1997), Filipino politician Gevaro Nepomuceno (born 1992), Curaçaoan footballer José Nepomuceno (1893–1959), Filipino film directors and producer Juanita Nepomuceno (1914–2000), Filipino lawyer and politician Paeng Nepomuceno (born 1957), Filipino bowler and coach Willie Nepomuceno, Filipino satirist and public intellectual
See also
Juan Nepomuceno, Spanish double given name Giovanni Nepomuceno, Italian double given name Nepomucký, a similar Czech surname