Osch and van Osch are surnames. Notable people with these surnames include:
Alphonse Osch (1909–1997), Luxembourgish politician Geoffrey Osch (born 1994), Luxembourgish alpine ski racer Henri van Osch (1945–2001), Dutch swimmer Kalia Van Osch (born 1993), Canadian curler Kesa Van Osch (born 1991), Canadian curler Matthieu Osch (born 1999), Luxembourgish alpine ski racer Suzzanna van Osch (1942–2008), Indonesian actress Ton van Osch (born 1955), Dutch military commander Yanick van Osch (born 1997), Dutch footballer