Campodonico is a surname of Italian origin, Campodonico being a hamlet of the municipality of Chiavari in Liguria, trading sea region of Northern Italy. Notable people with this surname include:
Amanda Campodónico (1879–1933), Argentine mezzo-soprano singer César Campodónico (1929–2005), Uruguayan actor Elida Campodónico (1894–1960), Panamanian teacher, women's rights advocate and attorney Esteban Campodónico (1866-1938), Italian-Peruvian medical doctor, university professor, and philanthropist Juan Campodónico (born 1971), Uruguayan musician, producer, composer, creator Mariano Campodónico (born 1974), Argentine football manager and former player Pablo Campodónico (born 1977), Argentine professional footballer Rodolfo Campodónico, one of the first composers of waltzes in Mexico Wally Campo (1923–2023), American actor born as Wallace Joseph Campodonico.