Heddle is a surname of Scottish origin.

People with the surname include:

John Heddle (1941–1989), British Conservative Party politician Charles Heddle (1812–1889), Scottish-Sierra Leonian businessman and shipowner Kathleen Heddle (1965–2021), Canadian rower Enid Moodie Heddle (1904–1991), Australian poet and writer for children Matthew Forster Heddle (1828–1897), Scottish physician and amateur mineralogist Ian Heddle (born 1963), Scottish footballer

Given name Heddle Nash (1894–1961), an English lyric tenor