Russek is a surname. Notable people with the surname include:
(born 1954), Mexican music composer Frank Russek (1875/1876–1948), Polish-born American businessman, co-founder of Russeks Russeks, ladies' fur and clothing department store in New York City, co-founded by Frank Jorge Russek (1932–1998), Mexican actor Louis Russek (1895–1985), American businessman; founder of Healthtex, a manufacturer of children's clothing Estelle Russek-Cohen, American biostatistician