N-Methylpiperazine is a heterocyclic organic compound.
Uses N-Methylpiperazine is a common building block used in organic synthesis. For example, N-methylpiperazine is used in the manufacture of various pharmaceutical drugs including cyclizine, meclizine, and sildenafil.
The lithium salt, lithium N-methylpiperazide, is used as a reagent in organic synthesis for protection of aryl aldehydes.
Synthesis Industrially, N-methylpiperazine is produced by reacting diethanolamine and methylamine at 250 bar and 200 °C.
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