Anguish refers to extreme pain, distress or anxiety.

Anguish may also refer to: Anguish (1917 film), a French silent film Anguish (1947 film), a Spanish crime film Anguish (1987 film), a Spanish-produced horror film Anguish (2015 film), an American horror film Anguish, the most famous painting of painter August Friedrich Schenck