Nájera is a surname. Notable people with the surname include:
Antonio Vallejo-Nájera (1889–1960), Spanish psychiatrist Ariel Castillo Nájera (born 1955), Mexican politician Carlos Antonio Reyes Nájera (born 1961), Guatemalan chess player Eduardo Nájera (born 1976), Mexican basketball player Elda Luna-Nájera, American social worker and politician Elisa Nájera (born 1986), Mexican TV host, model and beauty pageant titleholder Francisco Nájera (born 1983), Colombian footballer Fredy Renán Nájera (born 1977), Honduran politician José Manuel Nájera (born 1988), Colombian footballer Juan Carlos Nájera (born 1981), Guatemalan triple jumper and coach Lourdes Gutiérrez Nájera, American cultural anthropologist Manuel Nájera (born 1952), Mexican footballer Manuel Gutiérrez Nájera (1859–1895), Mexican writer and political figure Maricruz Nájera, Mexican actress Oscar Ramón Nájera (born 1950), Honduran politician Pedro Nájera (1929–2020), Mexican footballer Rosa María Avilés Nájera (born 1951), Mexican politician Rossana Nájera (born 1980), Mexican actress