Cisthene or Kisthene () was a town of ancient Lycia.
Its site is unlocated, but likely on the island of Kastellorizo, part of ancient Lycia, and the home of a lovely Lycian tomb. This is because Strabo mentions in his book Geographica that Cisthene/Kisthene was the biggest island opposite Antiphellus (i.e. Kastellorizo).
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