O'Neale may refer to:
Dion O'Neale, New Zealand applied mathematician Lila Morris O'Neale (1886–1948), American anthropologist and historian of textiles Rachid O'Neale (born 1991), Barbadian cricketer Royce O'Neale (born 1993), American professional basketball player Sarah O'Neale (née Thompson), fictional character from the Australian Channel Seven soap opera Home and Away Tug O'Neale, fictional character from the Australian Channel Seven soap opera Home and Away Walter O'Neale, D.D., Irish Anglican priest in the seventeenth to eighteenth century Benjamin O'Neale Stratford, 4th Earl of Aldborough (1746–1833), Irish peer and politician Margaret O'Neale Eaton (1799–1879), wife of John Henry Eaton, United States Senator and United States Secretary of War
See also O'Neale v. Thornton, 10 U.S. (6 Cranch) 53 (1810), a ruling by the Supreme Court of the United States O'Neal O'Neill Neale (disambiguation)